2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride

2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride - Names and Identifiers

Name	2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride
Synonyms	2-(3-(Trifluoromethoxy)phenyl)propan-2-amine 2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride
CAS	1314665-58-1

2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride - Introduction

2-(3-(trifluoromethoxy)phenyl)propan-2-amine is an organic compound with the chemical formula C10H14F3NO · HCl.

Nature:
-Appearance: White or off-white crystalline powder
-Melting Point: 125-129 ℃
-Solubility: soluble in water, high solubility; Can also be dissolved in alcohol and chlorinated hydrocarbon solvents
-Chemical properties: It is an amine hydrochloride compound with an amino group and a benzene ring structure, containing a trifluoromethoxy group.

Use:
-Drug research: It is used as an intermediate in drug synthesis and is widely used in research and development in the pharmaceutical field.
-Organic synthesis: It can be used for coupling, condensation and substitution reactions in organic synthesis reactions.

Method:
The preparation of 2-(3-(trifluoromethoxy)phenyl)propan-2-amine is generally accomplished by the following steps:
1.2-(3-(trifluoromethoxy) phenyl) acetone was reacted with excess anhydrous hydrochloric acid to give 2-(3-(trifluoromethoxy) phenyl) acetone hydrochloride.
2. Reaction of 2-(3-(trifluoromethoxy) phenyl) acetone hydrochloride with excess hydrogen ammonia solution gives 2-(3-(trifluoromethoxy) phenyl) propyl -2-amine free base.
3. Finally, the resulting 2-(3-(trifluoromethoxy)phenyl) propyl-2-amine free base is reacted with hydrochloric acid to form 2-(3-(trifluoromethoxy)phenyl)propan-2-amine hydrochloride.

Safety Information:
-This compound is organic and should follow regular laboratory procedures and safety regulations.
-It may be an irritating and corrosive substance and requires attention to protective measures to avoid inhalation, contact with skin and eyes.
-Wear appropriate personal protective equipment such as protective gloves, glasses and masks when in use.
-If contact or ingestion occurs, rinse immediately with water or seek medical advice.

Last Update：2024-04-09 21:00:56